![]() ![]() Median finger skin temperature (☌) increased by 44% (data pooled) with no significant differences between the groups. ![]() Nutritive blood flow (functional capillary density, capillaries.mm−2, measured at the dorsal side of the hand) decreased in the blocked extremity when adrenaline was used as adjuvant, from median (IQR ) 45 (36–52 ) to 38 (29–41 ), p = 0.028, whereas no significant change occurred without adrenaline. Median (IQR ) sub‐papillary blood flow increased substantially 30 min after the brachial plexus block, from 8.5 (4.4–13.5 ) to 162.7 (111.0–197.8 ) arbitrary units with adrenaline (p = 0.017), and from 6.9 (5.3–28.5 to 133.7 (16.5–216.7 arbitrary units without adrenaline (p = 0.036). Heart rate and arterial pressure were recorded continuously and non‐invasively. Microcirculation was assessed by laser Doppler fluxmetry (sub‐papillary blood flow), capillary video microscopy (nutritive blood flow) and continuous temperature measurements. In both sessions, they received an ultrasound‐guided infraclavicular brachial plexus block in the non‐dominant arm with 0.4 ml.kg−1 lidocaine, 15 mg.ml−1 with or without adrenaline 5 μg.ml−1. Twelve healthy, non‐smoking male volunteers were included, each attending two study sessions 2 weeks apart, and they were studied using a crossover design. We evaluated the effect of adrenaline on human skin microcirculation (nutritive and sub‐papillary) and systemic cardiovascular variables after it was added to lidocaine in infraclavicular brachial plexus blocks. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |